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Senior Scientist/Principal Investigator – Oncology-0900175 (Rockland, MA)
By | July 4, 2009
At EMD Serono, Inc. our strength is our people!
About the Company
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support systems to improve people’s lives. The company has strong market positions in neurodegenerative diseases, MS and endocrinology. EMD Serono is also a leader in fertility treatments. With a clear focus on the patient and a leadership presence in the biopharmaceutical industry, EMD Serono’s US footprint continues to grow, with more than 1000 employees around the country and fully integrated commercial, clinical and research operations in the company’s home state of Massachusetts.
Description
Expertise in oncology with focus on solid tumors, disease understanding to support drug discovery and translational oncology research.
Responsibilities
- The primary responsibilities of this position will be to provide scientific and strategic support in oncology research and to organize and manage project progression for small molecules and or/biologicals in pre-clinical development (or lead discovery)
- The candidate will be expected to plan, run, and present studies for multiple projects and assist project leaders in developing scientific and technical strategies in a matrix environment
- Other primary tasks include the development and implementation of phenotypic assays in tumor cells for mechanism of action studies, indication pin pointing studies to support clinical stratification plans, as well as performing assays to address drug combinations, with the overall goal of supporting discovery and pre-clinical development of lead molecules
- The candidate will also be expected to participate in the design and implementation of studies for the identification of biomarkers
- The candidate should provide expertise and knowledge in the area of cancer signaling and solid tumor cell biology
Education & Languages
- PhD with 2-4 years related industry/research experience preferred.
- Must be fluent in both written and spoken English.
Professional Skills & Experience
- Knowledge of signaling networks involved in cancer
- Expertise in phenotypic and mechanistic cell-based assays in solid tumor models: proliferation (monolayer and soft agar) and apoptosis assays, cell cycle profiling
- Expertise in the analysis of signaling pathway modulation in solid tumor models: Western analysis, FACS-based assays
- Expertise in testing drug molecules alone and in combination in tumor hallmark assays
- Experience in PCR and gene expression analysis is an asset.
- High level of computer literacy required, including familiarity with Excel and data analysis software
- Excellent written and oral communication skills
- Ability to effectively communicate and participate in multidisciplinary, cross-functional project teams
- Ability to work in a constantly changing environment
- Ability to manage research activities and balance working on multiple projects at once
- Excellent interpersonal skills
- Click the link below and open the door to the future by submitting your resume today!
- EMD Serono 0900175
