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Scientist III (Morrisville)
By | February 15, 2010
Essential Duties and Responsibilities:
This position is a bench scientist. Genetic analysis using the Affymetrix arrays (DMET, 3 IVT and whole transcript gene expression arrays). *Excellent skills in experimental design, implementation, troubleshooting, and data analysis. *Experience handling large datasets generated from DNA and/or Microarray analysis. *Performs RNA extraction, total RNA quality analysis and cDNA synthesis from a variety of sources including FFPE tumor samples using approved standard operating procedures. *Perform absolute and/or relative quantification of gene expression levels using real-time PCR methods. *Review of gene expression data, gene expression protocols and final reports. *Performs DNA purification and quantification, gel electrophoresis, and normalization. *Performs routine and non-routine genotyping assays including DNA sequencing, gel based assays and endpoint analysis. *Performs the laboratory portion of the assay design and development and validation process with including optimization of PCR conditions. *Assay design for the detection human genetic variations using bioinformatic software and other appropriate resources. *Perform literature searches in support of the scientific efforts at Gentris. *Develops protocols and methods for evaluating and analyzing various types of genomics data. *Assists in the writing, editing, and implementing standard operating procedures, material requirements documents, and other essential documentation. *Mentoring and training staff in the junior scientists positions. *Communicate ongoing project/study progress and act as the key interface to clients.
Minimum requirements include a Biological Science degree (BS+4, MS+2) with Industry experience, Biotech / Pharmaceutical / Drug Discovery. Candidates must have working experience with molecular biology techniques, and knowledge of advanced molecular biology techniques especially with RNA and microarray chip technology. Must be detail-oriented. Ability to think and work independently. Salary range $40-50K, commensurate with experience
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