Research Associate II, Molecular Biology (Job ID: 201009-320-24) (San Diego)
By | September 3, 2010
Genomatica is a chemical company that commercializes novel bio-manufacturing processes to produce a variety of industrial chemicals that impact all major industries and provide the materials that comprise the world we live in. The Company enables the production of sustainable chemicals through a compelling proprietary Integrated BioProcess Engineering Platform. Our unique capabilities fundamentally transform the way in which Nature can be leveraged to convert low cost feedstocks into high-value chemicals. These sustainable chemical products will benefit the world by reducing dependence on hydrocarbon feedstocks and improving the environment via safe, clean manufacturing processes.
Genomaticas Molecular Biology group is seeking an experienced, highly motivated Research Associate II to work with cutting edge Molecular Biology technologies to develop renewable chemicals. The successful candidate will join and support an interdisciplinary group of biologists dedicated to designing, discovering and optimizing novel of biochemical pathways. The group is involved in a milestone driven, proof of concept project with a goal of validating target genes that will ultimately convert renewable feedstocks into commodity chemicals. Strong technical, creative, organizational and communication skills are essential.
Responsibilities:
Conducting molecular biology experiments, including molecular cloning (DNA isolation, PCR, DNA mutagenesis, RT-PCR and Protein analysis)
Performing small scale experiments to test pathway enzyme activities (including enzymatic assays)
Continuous documentation, analysis and interpretation of experiments in the form of laboratory notebooks as well as timely entry of information into a LIMS database.
Presentation of analyzed and summarized results in both written and oral format and delivery of completed reports.
Work independently as well as collaboratively with other team members to accomplish project goals and milestones.
Qualifications:
Degree in bioengineering, molecular biology, biochemistry, or equivalent
BS/BA and 2+ years experience or MS degree, preferably in the biotechnology or pharmaceutical industry
Broad molecular biology expertise, and data management
Lab management experience desirable
Genomatica is committed to providing exciting career opportunities in a work environment that values trust, respect, openness, teamwork, creative talent, enthusiasm, and diligence. We are looking for innovative, motivated and uniquely talented people who enjoy the challenges and rewards of a burgeoning company devoted to commercializing cutting-edge technology.
Genomatica offers a competitive compensation and benefits package. To facilitate processing, please list the position Job ID in the subject line. Genomatica is an equal opportunity employer. No relocation is provided for this position.
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Research Assocaite (temporary approx. 8 months) (Sorrento Valley)
By | September 2, 2010
NovaRx is a biopharmaceutical corporation located in Sorrento Valley. Our mission is to develop therapeutic vaccines to cure cancer and enhance patient quality of life. We are currently looking for a Research Associate to work in our R&D Stem Cell department. The individual is responsible for performing cell-based assays to support our cancer vaccine program. The individual should be familiar with tissue culture, flow cytometry and immunological assays.
Responsibilities & Duties:
1. PERFORM CELL CULTURE, TRANSFECTION, FLOW CYTOMETRY ANALYSIS (FACS), ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA) AND CELL-BASED IMMUNOLOGICAL ASSAY.
2. Record experimental procedures and results accurately and clearly in lab notebooks.
3. Comply with company safety policies and minimizes risk to self, others and the environment, consistent with the community and industry standards.
4. Actively pursue corporate timelines and milestones set by the department director and upper management.
5. Other duties as assigned.
Requirements:
1. A Bachelors or Masters degree in the biological sciences with a minimum of at six years cancer immunology experience.
2. Strong technical background in cell biology and immunology. Experience working with cell culture, FACS and ELISAs.
3. Familiarity with Word, Excel and Powerpoint..
4. Knowledge and experience with DNA immunochemistry techniques and PCR is a plus.
5. Experience in GLP and experimental procedures record keeping requirements.
6. Demonstrated dedication, communication and teamwork are essential.
7. Ability to work independently with minimal supervision in a team based environment.
8. Good verbal and written communication skills.
9. Ability to work calmly and effectively in a fast paced, dynamic environment.
LOCAL CANDIDATES ONLY. THIS IS A TEMPOARY POSITION FOR APPROXIMATELY 8 MOTHS. MAY BE EXTENDED.
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SENIOR RESEARCH ASSOCIATE-LEADERSHIP ROLE (SAN DIEGO, CA)
By | September 1, 2010
Sapphire Energy was founded with one mission in mind: to change the world by developing a domestic, renewable source of energy that benefits the environment and hastens Americas energy independence. Sapphire Energy is a venture capital backed company developing next generation biofuels, based on recent advances in metabolic engineering. The companys focus is the commercialization of high performance, low cost, and low carbon footprint biofuels or what we like to call Green Crude. The goal is to replace conventional gasoline, diesel, and jet fuel.
From the start, our goal has been ambitious: to become the worlds leading producer of renewable fuels and petrochemical products and now we are on the verge of creating a whole new industry we hope you will join us!
We are seeking a Senior Research Associate for a leadership position in our San Diego Upstream group.
Responsibilities include, but are not limited to:
Design and execute experiments to modify microbial metabolism, including high-throughput cloning and expression analysis.
Develop assays and criteria for characterizing modified microorganisms.
PCR, cloning, and sequence analysis.
RNA purification and cDNA library preparation.
SDS-PAGE and Western blotting.
Manage team research projects in the short and long term,
Make and record detailed observations, analyze data, and interpret results on an ongoing basis.
Work within a team in order to achieve departmental milestones.
Requirements:
Bachelors or Masters degree in biology, microbiology, molecular biology, or related field, plus at least 7 years of applicable industry experience.
2+ years proven successful experience in a team leadership/management position
Exceptional organizational and time management skills.
Demonstrated ability to independently design, execute, troubleshoot and interpret data and experiments.
Creativity and the ability to work in an interdisciplinary team in order to achieve technical and business milestones.
High quality interpersonal and communication skills are extremely important.
Proficiency in writing and oral presentations.
Sapphire offers very competitive compensation packages including bonuses and equity, as well as full benefit packages, which include health, dental, vision insurance, 401k, and paid time off.
LOCAL SAN DIEGO CANDIDATES SEND RESUME DIRECTLY TO:
Karen Wise
Senior Recruitment Consultant for
Sapphire Energy
No Third Party Recruiters
No Phone Calls Please
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Research Associate – Clinical Molecular Biology
By | August 30, 2010
Research Associate – Clinical Molecular Biology
Essential Duties and Responsibilities
* Perform validation of new clinical molecular assays using PCR, DNA sequencing and other modern molecular analysis techniques.
* Perform quality control activities including incoming reagent qualification, instrument performance verification, temperature monitoring, pipette calibration, etc.
* Support clinical specimen testing and reporting to pathologists.
Qualifications
* Strong background in molecular biology techniques (standard and real-time PCR, DNA sequencing, automated nucleic acid isolation, etc).
* Thorough understanding of theory and operation of instrumentation used in molecular analysis.
* Knowledge of statistical methods pertaining to assay quality control is desirable.
* Ability to problem-solve and work independently as well as in a team environment.
* Excellent written and oral communication skills.
* Proficient with Microsoft Office, particularly Excel, to produce charts, graphs and spreadsheets.
Education and Experience
* Bachelors or Masters degree in biology, biochemistry or molecular biology, or related science field.
* 5+ years of relevant experience.
* Experience in clinical laboratory science, or qualification as a licensed Clinical Molecular Genetic Scientist is a plus.
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UCSD – Staff Research Associate II – 52268 (La Jolla)
By | August 24, 2010
To Apply: http://jobs.ucsd.edu/bulletin/job.aspx?cat=research&sortby=post&jobnum_in=52268
Apply By: 9/1/10
DESCRIPTION:
Perform experiments using a variety of standard molecular biology procedures concerning the role of hypoxia and tumorigenesis. Analyze the effect of potential HIF inducers on HIF target gene expression and conduct in vivo and in vitro experiments. Conduct experiments to isolate DNA and RNA from cultured mouse embryonic fibroblasts and astrocytes. Assist in writing papers, manuscripts, journal articles, and proposals for research. Manage laboratory, including providing work direction and training for undergraduate lab assistants, ordering supplies and equipment, serving as safety coordinator and other duties related to laboratory administration.
~~Occasional overtime (evening or weekend) may be required by particular experiments.
~~Must safely handle and store chemicals, biochemicals, hazardous chemicals, biohazardous materials and radioactive materials.
QUALIFICATIONS:
* Demonstrated strong theoretical knowledge of Anatomy, Physiology, Genetics, General Chemistry and Biochemistry acquired through a combination of extensive study and experience.
* Strong experimental background in molecular biology techniques applicable to studies involving mice, embryonic and adult models. Experience in handling and culturing mouse embryonic fibroblasts.
* Ability to perform DNA replication including radioactive labeling, immunostaining of fluorescent tagged DNA within nuclei, quantitative immunofluorescence, nuclear isolation, and DNA isolation.
* Ability to perform PCR, protein purification, Western blotting and immunoprecipitaion, and gel electrophoresis techniques isolating RNA.
* Knowledge of experimental tumorigenesis. Knowledge of in vivo and in vitro tumor growth to analyze growth regulation, vascular density and necrotic regions.
* Knowledge of MSDSs, hazard communication, and Injury and Illness Prevention Program safety precautions including appropriate clothing and shoes; safe storage and handling of chemicals and biohazardous materials; and use of protective items such as gloves and goggles.
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Research Associate
By | August 19, 2010
Research Associate
Must have the following experience
* Working with multi-well, plate-based assays such as PCR, ELISA, drug screening, etc. and the ability to handle large numbers of samples in an organized manner
* Minimum of 1 years experience with mammalian cell culture
* Q-PCR (QPCR)/Real-time PCR
* Use of Microsoft Excel for data analysis
* The ability to function independently as well as work on coordinated projects as part of a team
Preferred experience
* Culture of hematopoietic cells or stem cells
* Experience with magnetic-based cell separation technologies
* Use of non-PCR DNA amplification technologies (e.g. Phi-29)
* Identification and/or isolation of rare cell populations including methods of magnetic-bead based separation
* Flow cytometry/FACS for analysis and/or sorting
Requirements
Bachelor’s degree and relevant experience required. Masters degree desired. Excellent written and verbal communication skills required. Ability to work in a startup environment.
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Research Associate/Senior Research Associate #1021
By | August 19, 2010
Research Associate/Senior Research Associate Positions
Tanabe Research Labs (TRL), www.trlusa.com, is an independent subsidiary of Mitsubishi Tanabe Pharmaceutical Corporation, a major Japanese pharmaceutical company. The TRL research facility has been operating in San Diego in the heart of the biotechnology community for the last 20 years. Recently TRL refocused its strategic direction towards biological research and is building up a new research team with an emphasis on immunology and molecular biology. TRL is seeking highly motivated and skilled Research Associates to work in an immunology group for the pre-clinical development of novel biologics for the treatment of autoimmune and chronic inflammatory disorders. If you are looking for an opportunity to help build new programs and be part of a fresh new team with a bright future, TRL is a company you should consider.
Responsibilities:
The major responsibilities include the generation/identification of therapeutic alternative scaffold proteins or antibody mimetics. Individuals would be responsible for helping to establish immunological models and assays for the testing of therapeutic proteins. In addition the successful candidates would be responsible for all aspects of conducting a scientific study using standard molecular or cell biology techniques.
Requirements:
The positions require a BS or MS in the biological sciences with a minimum of 3 years of laboratory experience, preferably in the pharmaceutical industry. The candidates must have experience in immunological techniques such as ELISA, flow cytometry, cell culture, in vitro immunological assays and protein handling. Prior experience with cytokines and/or other immunologically important molecules including monoclonal antibodies is important. The candidates should also have experience in basic molecular biology techniques such as DNA and RNA preparation, PCR , transfection, etc. Excellent communication skills, the ability to work in a goal and team-oriented setting, well developed organizational skills, the flexibility to participate in several projects simultaneously and the ability to thrive under pressure are also required
Qualified candidates should send their resumes to hr@trlusa.com
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Research Associate (San Diego)
By | August 19, 2010
The Proteogenomics Research Institute for Systems Medicine is a non-profit organization dedicated to finding novel treatments to cure cancer and other diseases. A position is available immediately for a motivated research associate to join our team in the antibody discovery and protein engineering group. The candidate will conduct research in an innovative technology-driven program to identify protein targets and antibodies for immunotherapy of cancer. The position requires a BA/BS in biological sciences; prior experience in molecular biology is required; knowledge and hands-on in phage display, hybridoma technology, PCR, recombinant protein expression, Western analysis, and/or ELISA is a plus.
Please send your resume and cover letter to the above email address.
Thank you.
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Temporary Research Associate (San Diego, CA)
By | August 19, 2010
Sapphire Energy is a venture capital-backed company developing next generation biofuels based on recent advances in metabolic engineering. The companys focus is the commercialization of high performance, low cost, and low carbon footprint biofuels that are direct replacements for conventional gasoline, diesel, and jet fuel.
We are seeking an exceptional Temporary Research Associate to join our Microbiology / Molecular Biology staff in San Diego, CA.
Requirements:
Bachelors degree in biology, microbiology, molecular biology, or related field, plus at least 1 year of applicable experience.
An understanding of microbial genetics is essential. Experience with unicellular algae a plus.
Strong organizational skills.
Critical thinking and problem solving skills.
Ability to work in an exciting and demanding environment to meet aggressive deadlines.
Demonstrated ability to independently design, execute, troubleshoot and interpret experiments.
Ability to participate in interdisciplinary teams.
Due to the highly collaborative nature of this position, interpersonal and communication skills are extremely important.
Responsibilities include, but are not limited to:
Growing and maintaining cultures, sterile technique and other microbiology techniques are essential job functions; examples include titering cultures, mutagenesis and mutant selection / screening, transformation / electroporation, flow-cytometric analysis.
PCR, cloning, sequence analysis and other nucleic acid-based molecular biology techniques. Optimization of standard molecular biology techniques will be important.
Make and record detailed observations using a microscope.
Analyze data, and interpret results.
This is a temporary position expected to last 6-10 weeks. To apply, please send your CV and salary requirements to human.resources@sapphireenergy.com and reference Temp RA in the subject line.
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Laboratory Technician (La Jolla)
By | August 19, 2010
The Salk Institute for Biological Studies is currently seeking a Laboratory Technicain for the Genomics Analysis Lab, under the direction of Dr. Joe Ecker. Lab research focuses on functional genomics studies, using the reference plant Arabidopsis thaliana, with a biological focus on understanding hormone signal transduction pathways.
Research and lab responsibilities may include:
Extract DNA from plant tissue using High Through Put assay (chloroform/precipitation) for PCR genotyping
Loading PCR product to High Through Put gel electrophoresis.
Seed collection, seedling transplanting, tissue extraction, and homozygous plant selection
Lab maintenance and upkeep.
Education: Molecular Biology or related Biology or Chemistry coursework is required. Related degree is preferred.
Experience: Previous lab experience preferred but not required. Proficiency with MS Office Suite (Excel, Word, Power Point). Dependable with ability to work with minimum supervision is necessary, as well as attention to detail, verbal communication and well organized.
Special Requirements: Ability to work a flexible schedule to meet research needs is required. Ability to maintain focus while performing repetive tasks is essential.
Physical Requirements: Close mental and visual attention required for periods of time. Time spent intermittently standing and sitting. Must be able to lift and/or carry up to 20 lbs.
Apply on-line at http://www.salk.edu/careers/
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