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Research Assistant / Technician - Dana-Farber Cancer Institute (Longwood Medical Area)

By | December 22, 2008


Job Summary

Duties and Responsibilities:

A new laboratory being formed by Rameen Beroukhim at the Dana-Farber Cancer Institute seeks a research assistant to join in efforts to apply cutting-edge genomic technologies to determine optimal treatment strategies for patients with brain and other cancers. The aim of these efforts will be to initiate and conduct clinical trials in which the genomic features of patients and their tumors are robustly determined and used to fashion rational treatment. To that end, the individual will engage in experiments involving genomic DNA/RNA isolation from cancer tissue, preparation for microarray analyses, and nucleic acid amplification. The predictive value of these genomic assays will also be assayed in laboratory-based model systems, for which the individual will engage in functional experiments that apply cell culture techniques, recombinant DNA and gene transfer methods, and other cell biology assays (Western blots, immunoprecipitation, etc.).

Job Qualifications

Required Education, Experience, and Skills:

A minimum of a Bachelors Degree or equivalent is required, preferably in the Biological or Biochemical Sciences. Prior research experience in pathology, molecular biology, or genetics is preferred. In particular, experience with tissue (histological examination and dissection), DNA/RNA purification, PCR amplification, subcloning, or retroviral transfection is a plus. The ideal candidate will be comfortable in a team environment, enthusiastic about scientific discovery, and highly self-motivated. A minimum two-year commitment is required.

Schedule

Full-Time


Qualified candidates should e-mail or send a hard copy of a cover letter, resume, and the complete contact information for at least two references.

Hard copies may be sent to the following address:

Dr. Rameen Beroukhim
c/o Mr. Michael A. Donohoe
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM 1036
Boston, Massachusetts 02115

Topics: Boston Biotech jobs | No Comments »

Microbiologist (San Diego)

By | December 17, 2008

MICROBIOLOGISTS

A -TEK, a leading Government Contractor, has exciting career opportunities for results-oriented laboratory professionals in various locations nationwide. We are currently seeking experienced Microbiologist to perform a variety of molecular (particularly PCR) and biological tests to identify the presence of pathogenic microorganisms/agents.

EMPLOYEE BENEFITS:

The individual hired for this position would be eligible to participate in our rich benefits package which includes approximately 90% employer-paid premiums for all employee coverage. The company also supplements the premium payment for spouse and/or dependents coverage under each of the health-care insurance plans only. Most benefits are effective on the first of the month following the date of hire. The following outlines the benefits provided to full-time employees:

• Medical Insurance and Prescription Benefits – 3 Plan Options available under Anthem BC.BS PPO

• Dental Insurance – 2 Plan Options under SunLife

• Vision Insurance (Vision Service Plan)

• Life Insurance (1x annual salary up to $100k max)

• Accidental Death & Dismemberment Insurance (1x annual salary up to $100k max)

• Long-Term Disability

• Short-Term Disability

• Professional Development/Tuition Assistance/Professional Associations ($10,500 per year)

• 401(k) Plan

• Premium Only Plan

• Paid Leave beginning at 15 days per year

• Paid Holidays at 10 days per year

• Direct Deposit in up to 3 different accounts

POSITION DESCRIPTION:

Individuals will be responsible for:

• Perform a variety of non-research biological science work utilizing microbiological and molecular techniques, including DNA extraction and read-time polymerase chain reaction (PCR) including handling, receipt, and processing of samples, containing potentially high hazard biological agents.

• Assuring that incoming specimens are recorded, processed, and triaged appropriately while maintaining “chain-of custody”.

• Reporting test results to appropriate individuals using established procedures.

• Applying knowledge of these advanced molecular techniques and microbiological procedures to appropriately interpret and report the findings of the assays.

• Performing quality control and quality assurance procedures including, but not limited to routine equipment maintenance and calibration, and documentation of quality control and quality assurance activities as needed. Ensuring that reagents, supplies and equipment are adequately maintained.

• Maintaining documentation collection on findings and protocols.

• Providing laboratory support for field responses and investigations as directed.

• Reporting test results to appropriate individuals using established communication protocols with Local, State and Federal agencies.

Individuals must be available for rotating schedule that provides coverage for a “24hours/7 days a week” laboratory operation.

This position routinely works 2 or more weekends per month as directed.

REQUIRED QUALIFICATIONS :

Knowledge of established scientific methods and techniques of microbiology to perform recurring assignment of moderate difficulty (i.e. the methods and techniques are well established, apply to most situations encountered and do not require significant deviation from established methods) or discrete portions of the complex projects.

• At least one year “laboratory bench” experience performing research or diagnostic PCR testing (includes nucleic acid extraction methodology, set up and analyses of real time PCR assays, detection and determination of DNA contamination events).

• Minimum one year “laboratory bench” experience performing research or diagnostic PCR testing (includes nucleic acid extraction methodology, set up and analyses of real time PCR assays, detection and determination of DNA contamination events).

• Knowledge of biohazard regulations in the proper and safe handling and transport of materials containing virulent and pathogenic disease agents and toxicants.

• Knowledge of chain–of–custody regulations and procedures.

• Basic knowledge of computer systems methods and applications, including word processing, statistical data management software packages.

• Experience in the use of, laboratory instrumentation related to cellular and molecular biology.

• Experience maintaining Quality Assurance and Quality Control Documentation and organizational records to ensure adequate reagents and material for 24/7/365 operation.

EDUCATION:

A Bachelors degree from an accredited University in Microbiology, Molecular Biology or related course work in Biological Sciences and at least one year of laboratory bench experience, utilizing polymerase chain reaction (PCR) technology, aseptic techniques and biological assays. Alternatively, equivalent biological laboratory bench experience for at least 4 years is acceptable.

BACKGROUND INVESTIGATION:

• Requires passing a law enforcement background check.

• May require specific state certifications to work in Public Health facilities, registration with the CDC Select Agent Program, and passing of a Department of Justice background check.

• Individual selected will be subject to a background investigation and must meet eligibility requirements for access to sensitive information. The position may require a SECRET clearance.

• U.S. Citizenship required.

RESUME SUBMISSION REQUIREMENTS:

1. Submission MUST include your Salary requirement (either as specific amount or acceptable range).

2. Include a reference to job # MCRO - CL1100

3. EMAIL your Resume to LabJobs@a-tek.net or FAX to 703-669-1109.

A-TEK, Inc. is not a recruiting agency

and will not disclose any of your personal information to any outside party.

EOE/M/F/V/D

Topics: San Diego Biotech jobs | No Comments »

Assay Development Scientist (lower pac hts)

By | December 16, 2008

Assay Development Scientist

Linkage Biosciences Inc is seeking an outstanding scientist to develop PCR-based assays for our proprietary and leading edge molecular diagnostics products. The successful candidate will have a strong background in human genetic assay development and a desire to be part of an exciting, growing company.

Responsibilities include:

• Develop, optimize, and determine feasibility of new assays

• Work independently and within project teams to design, perform, and analyze experimental studies

• Work with software teams to develop and deliver user interface systems and bioinformatics tools

• Collaborate to develop robust manufacturing processes and procedures

• Develop and track project plans to meet milestones

• Maintain detailed records and documentation

Requirements:

• Ph.D. in Molecular Biology or closely related field

• 3+ years, post Ph.D. experience in progressively more responsible MDx R&D positions

• 2+ years of commercial diagnostic, PCR-based assay R&D

• Experience and broad knowledge of human molecular diagnostic assay technology and targets, including human SNP assays.

• Successful project management experience

• Detail oriented and self-motivated

• Previous experience supervising others would be a plus

Please see our website for additional background on the company: www.linkagebiosciences.com

Applicants should send their CV summarizing qualifications and experience, including three references, to:

Human Resources:

hr@linkagebio.com

Or send to:

Linkage Biosciences Inc

Attention: Human Resources

2503 Bush Street

San Francisco, CA 94115

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Staff Research Associate I (San Francisco, CA)

By | December 16, 2008

NCIRE - The Veterans Health Research Institute. Our mission is to advance veterans health through research. We are the largest nonprofit research institute associated with the Department of Veterans Affairs. We conduct research in many fields, including mental health, neurological disease, cardiovascular disease, cancer, bone disease, infectious diseases including HIV, and improving patient care.

NCIRE currently has an exciting opportunity for a Staff Research Associate to conduct research experiments evaluating the mechanisms by which HIV protease inhibitors affect glucose and lipid metabolism by using stable isotope tracer techniques.

Essential Functions:

• Prepare human blood samples for analysis by gas chromatography/mass spectrometry

• Prepare various chemicals for experiment use, including buffer solutions

• Conduct standard biochemical and/or enzymatic assays

• Maintain established mammalian cell lines

• Perform experiments using routine molecular biology techniques such as nuclear acid purification, reverse transcription reaction, and quantitative PCR

• Maintain detailed written record of work performed

• Perform analysis of experiment results and findings, including data collection, entry, statistical analysis and graph creation

• Perform supply ordering/maintenance

• Perform equipment maintenance

• Perform additional general laboratory management duties as assigned

• Perform other duties as assigned

Job Requirements:

• B.A./B.S. in biology or related field

• Strong oral/written communication and organizational skills

• Ability to accurately follow experimental protocols

• Ability to manage multiple projects, tasks and priorities to achieve desired goals

• Prior experience in a laboratory environment and basic knowledge of gas chromatography/mass spectrometry and procedures used in biology research highly desirable.

Please apply online by visiting: http://jobs-ncire.icims.com/jobs/1275/job and include cover letter and salary expectation.

NCIRE offers a competitive compensation and generous benefits package, a stable, exciting environment and a wonderful work/life balance.

For more information about NCIRE please visit us at www.ncire.org.

NCIRE is an Equal Opportunity Employer

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Jr. Technical Project Manager — Digital Publishing (Boston, Backbay)

By | December 15, 2008

Job Summary:

We are seeking an experienced technical project manager to work directly with the program manager in a technical consulting role. The project manager will determine with PM how issues/risks will be tracked, documented, & communicated; ensure that all Business Requirements are aligned with the Chartered scope; establish a Technical Analysis Plan and determine the tool(s) that will be used, and the artifacts that will be delivered, as part of the Technical Analysis; review the technical analysis documentation for functional completeness with the Solution Architect; signoff on the Artifact Approval Summary for Technical Analysis; work directly with the Designer and/or Data Analyst to ensure all appropriate high level design documentation is created; coordinate the review of the high level design with the architect, and obtain the architect’s approval on the Artifact Approval Summary; define High level testing strategy; complete the necessary forms (websites, databases, security); request testing environments and manage them; manage development deliverables; tracking Project Change Requests (PCR); coordinate changes to production code; initiate creation of the Implementation / Release Notes (cutover / handover doc); project development information document created; code reviews completed (signoff on Artifact Approval Summary); ensure that all SOX considerations have been addressed; implementation Planning; run the point for any technical issues during the warranty period.

Experience or exposure to Java web development environments, Windows and Unix servers, Spring, Oracle, & Macromedia Flash.

This coordinator should be self-motivated and self-directed.

Knowledge, Skills and Abilities Required

• High level of adaptability to changing requirements and willingness to learn new skills

• Strong interpersonal skills and ability to deal effectively in a team environment

• Excellent relationship building skills

• Meticulous attention to detail and adherence to deadlines are essential

• Ability to work independently and prioritize work

• Proactive multi-tasker who can manage details in a fast-paced, deadline-driven environment;

• Analytical and problem solving skills

Education & Experience:

• Bachelor’s degree preferred, but not required

• 2 - 5 years experience in project coordination

• Organizational and computer skills, including Microsoft Project, Excel, Word, and Outlook

ABOUT US

Xplana Learning is committed to providing meaningful educational experiences to people all over the world. Our goal is to create educational software that allows teachers to focus on teaching, and students to concentrate on learning. We believe that while technology is a key component in instructor and student success, it should blend with human touch and imagination rather than disrupt them. Our strategy is based on the creation of learning experiences that can be stored, retrieved, and repurposed or displayed in a variety of platforms.

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UCSF Staff Research Associate I (inner sunset / UCSF)

By | December 15, 2008

Job Summary

Incumbent will be responsible for maintaining and managing a molecular biology lab and for performing cell culture, mRNA and protein expression analysis including nucleic acid isolation, regular and real-time PCR and Western blotting analysis. Establish tumor xenograft animal models. Oversee the work and training of students and staff; and perform other duties as assigned. This position offers excellent opportunities for intellectual growth and training in a brand new field of RNAa technologies.

Required Qualifications

BA/BS with a degree in Biochemistry, Chemistry or related science and two or more years of recent, directly related work experience following degree completion, utilizing the techniques or methods required by the position and demonstrating technical expertise in these areas; or an equivalent combination of education and experience; significant experience in tissue culture work; excellent sterile techniques; skill in small animal manipulation, ability to carry out microarray experiments; experience in cell and molecular biology, including flow cytometry, PCR, cloning, sub-cloning, mutagenesis, preparation and manipulation of DNA, quantitation and agarose electrophoresis; experience in protein expression analysis; comfort working with instrumentation and computers; maintenance of accurate notebooks and computer files; team player with good communication and interpersonal skills; willingness to learn, seek out advice and admit errors; highly motivated to succeed.

Location: Parnassus Campus and Mission Bay (after 2009.3)

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UCSF - Staff Research Assoc. Oral & Maxillofacial Surgery (inner sunset / UCSF)

By | December 12, 2008

Full Time position as UCSF SRAII includes benefits, vacation, sick leave and paid holidays.

Location: Parnassus Campus

This position will be located in a clean, well-equipped laboratory on the Parnassus campus. Under the direction of a surgeon, the successful applicant will conduct an innovative research project evaluating oral and facial function in animal models. The position involves the production of a mouse cancer model, evaluation of rodent behavior, preparation and administration of pharmacologic agents, and isolation of DNA and RNA from tissue specimens. Experience and skill with rodents, cell culture techniques, drug preparation, immunohistochemistry and PCR are useful. Responsibilities will include handling rodents, monitoring rodent behavior, tissue processing, PCR analysis, data collection, purchasing and inventory of laboratory supplies. The successful applicant will also be involved with translational work and will be responsible for the collection and management of biofluids (dialysate, blood, saliva) from cancer patients. Administrative skills are required.

REQUIRED

A minimum of a BA or BS in biological sciences. Knowledge of DNA and RNA isolation, PCR and immunohistochemistry. Good organizational skills and computer skills. Ability to work flexible hours including weekends.

PREFERRED

Previous experience in a research laboratory. Experience with rodents.

Please apply online at http://ucsf.ucsf.edu/careers/ Req. # 29136BR

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Technical Assistant (Broad Institute of MIT and Harvard) (Cambridge - near the Kendall T stop)

By | December 11, 2008

The Broad Institute of MIT and Harvard seeks a TECHNICAL ASSISTANT, Broad Institute-Medical and Population Genetics Program (MPG), to work with a multidisciplinary team focused on elucidating the genetic basis of complex disease. Specifically, experiments will involve high-throughput SNP genotyping and emerging DNA sequencing technologies and the employment of cutting-edge genetic methodologies and analytical strategies. Will work on disease studies related to Crohn’s disease, Type 2 diabetes, autism, and various mouse genetics projects. Experiments will include setting up high-throughput SNP genotyping and sequencing using robotics; engaging in analysis of genetic SNP data; assisting in validating novel loci; preparing, handling, and tracking patient DNA samples for various disease projects; and DNA preparation, whole genome amplification and purification, PCR, and gel electrophoresis. Will perform related duties as requested.

REQUIREMENTS: a bachelor’s degree in biology or related field; at least one year of experience in a molecular biology laboratory or on an independent research project; familiarity with basic molecular biology and sterile techniques and with the operation of standard lab equipment; excellent analytical and communication skills; and ability to interact professionally with staff at all levels in a dynamic and collaborative environment. Excellent organization and time management skills and the ability to balance a variety of project goals required. Must be independent and comfortable working on multiple genetic analysis projects at various stages and levels of involvement. Knowledge of fundamental genetic principles and computational approaches a plus.

Interested applicants may apply online at http://www.broad.mit.edu/info/careers/ and reference job number MIT-00006149. Please indicate that you located this position on Craigslist.org

PROFILE: the Broad Institute was founded to empower scientists of all kinds to work together on difficult, diverse, critical genomic and biomedical challenges. The Institute offers comprehensive benefits including:

* Competitive pay

* Medical, dental, life insurance plans

* 401(k) plan with matching contributions

* Tuition assistance plan

* Four weeks of vacation after one year

* T-Pass subsidy program

Topics: Boston Biotech jobs | No Comments »

Account Executive - Sales/Recruiting (Clayton NC)

By | December 11, 2008

NSTAR Search Account Executive

At NSTAR Global Services, our purpose is to strategically partner with our clients to achieve breakthrough results. We have built our reputation for excellence by providing a variety of world class service solutions to the greatest equipment manufacturing firms in industry. We work closely with them to make sure that they have the resources they need whenever they need them – anywhere in the world.

To build on this success, we are currently seeking individuals to join our staff in Clayton, NC, to work in the role of Account Executive. Working in inside sales, the Account Executive will take a lead role in identifying new clients and developing account relationships.

If you want to be part of a success-oriented organization, are goal oriented and have proven your ability to produce in a high call volume environment like sales, agency recruiting, customer service, or telemarketing, you want to talk to NSTAR.

Duties and responsibilities:

• Sales and Territory Management Planning (15%)

– Develops sales plan for assigned existing and targeted accounts.

– Analyzes and assimilates industry and competitive information.

– Researches targeted prospects and formulates contact strategies

– Meets monthly, quarterly and annual sales objectives

• Executes the Sales Plan (75%)

– Executes the sales plan and tracks performance of closed business.

– Conducts research to identify prospect needs.

– Contacts 100% of assigned customers each quarter.

– Designs customer-specific, value-based solutions to meet clients’ business and performance improvement needs.

– Acts on sales leads within 24 hours of receipt and provides status report.

– Involves and positions others from within the NSTAR team with key clients early in the sales cycle.

– Presents articulate sales proposals to client decision-makers and closes opportunities that meet clients’ stated goals.

• General Administrative and Other Responsibilities (10%)

– Updates PCR system with all customer data and sales activities.

– Prepares monthly revenue forecasts.

– Fully knowledgeable about all available NSTAR programs and services.

– Knowledgeable of the competition and skilled at competitive selling.

– Identifies training needs and schedules time for learning & development.

Desired Qualifications:

• B.A./B.S. (or equivalent)

• 2+ years experience in agency recruiting; sales; telemarketing or customer service with a high call volume.

• Strong Communication Skills

• Goal Oriented

TO APPLY:

If you wish to be considered for this position, email your resume with salary requirements to Rosalind Goldsmith at rgoldsmith@nstargs.com

FOR MORE INFORMATION:

For more information, Check out our website at www.nstargs.com

Topics: Raleigh-Durham PCR jobs | No Comments »

Sr. Scientist (petaluma)

By | December 10, 2008

Company Overview

Eurofins US is a commercial laboratory network with several locations throughout the United States. Our scientific staff has many years of experience with a broad range of laboratory methods from wet chemistry to Real-time Quantitative PCR to microbiological analyses. Our goal is to be the bioanalytical company of choice for the US food, feed, pet food, animal health, dietary supplement, pharmaceutical, and biotech industries.

Job Description

Continually strive to improve the quality of work we provide to our clients through method development, verification and modification of new and or existing methods for all Business Units with the U.S. Food Division.

Oversee timely and accurate analysis of samples to meet customer commitments. This includes, but is not limited to, sample preparation for sample analysis, data review and reduction, and providing data interpretations and opinion.

Participate in the daily lab operations including: process control, continuous quality improvement, innovation through information technology. Ensure all regulatory procedures pertaining to sample testing are followed correctly.

Assist in the technical conduct, quality control, and related record keeping of all analytical evaluations performed.

Ensure that all pertinent company health, safety, and environmental programs are adhered to and documentation is maintained.

Establish and maintain professional business relationships with clients, industry officials, and peers.

Assist in the generation of marketing strategies. Create and review literature for marketing new methods and instrument capabilities to clients.

Represent the laboratory in technical meetings.

Participate with the Sales/Marketing team in the preparation and quotation of major technical studies.

Understand and follow each Quality System document relevant to employment responsibilities, e.g., methods, SOPs, etc. Propose changes to documents and approve documents when required.

Other duties as assigned.

Education and Experience

-Bachelor’s degree in Science or related field, PhD or Masterspreferred, and 5 – 7 years of applicable and progressively expanded laboratory experience. Strong technical and management background required. Natural products chemistry a plus.

-Experience in laboratory procedures, data analysis, computer operations, mathematics, and technical/business writing. Proven ability to work in a cGMP environment.

-Knowledge and experience of ISO systems

Topics: Bay Area Biotech jobs | No Comments »

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