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Associate Scientist (Level II) (Cambridge, MA)
By | March 2, 2010
An Associate Scientist (Level II) will work in the Research Biology Department at the ALS-Therapy Development Institute in Cambridge, MA to support in vivo and in vitro validation of candidate therapeutics in murine models of Amyotrophic lateral sclerosis (ALS). This candidate will be responsible for the following three jobs:
1. Weekly genotyping of transgenic mice using an in-house, automated Q-PCR platform.
2. Support and development of enzyme linked immunosorbent assays (ELISA) for weekly, large-scale pharmacokinetic studies.
3. Development of assays for protein characterization such as immunoblots, immunoprecipitation, and immunohistochemistry.
The candidate will work closely with internal in vitro and in vivo research teams, as well as external vendors, to support ongoing preclinical studies in a mouse model of ALS.
Academic Qualifications and Technical skills:
The candidate must have a BS or MS in biology, biochemistry, or molecular biology and 3+ years of experience in molecular biology techniques including nucleic acid purification, PCR, Q-PCR, ELISA, and immunoblotting. Working knowledge of spreadsheet programs, is also required. Ideally, the candidate will have experience with molecular biology automation.
Strong communication skills and a team orientation are essential.
The Amyotrophic Lateral Sclerosis Therapy Development Institute (ALS-TDI) is a non profit biotech focused on the discovery and development of therapeutics to treat ALS. The institute is a world leader in the pharmacological testing of lead candidates in animal models of ALS and has established expertise in the utilization of genomics and proteomics technologies for drug discovery.
Please submit resume and cover letter.
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