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DNA2.0 is a rapidly growing synthetic biology company and is today the largest US provider of synthetic genes. We now seek a research assistant/associate to support our gene manufacturing group. The company has an exciting and dynamic work environment with many opportunities for personal and corporate growth.
The position entails synthetic gene manufacturing within a dedicated team. The work includes following standard operating procedures for gene synthesis, molecular biology methods and DNA Sequencing. The individual will also interact with our bioinformatics department.
The candidate should have broad, demonstrated skills in molecular biology, particularly in the areas of PCR, cloning and DNA sequencing analysis. Experience with automated liquid handling stations, DNA synthesis platforms and basic programming skills are a plus. The candidate will be hands on, possess excellent communication and organization skills, strong interpersonal skills, a desire to work in a team environment, the ability to contribute intellectually to the projects, and the ability to complete projects under strict deadlines. The ideal candidate should, furthermore, be comfortable working in a fast-paced setting while retaining impeccable organizational skills.
Requirements:
Qualified candidates will posses a Bachelors degree in Biology or related field with molecular biology/biotechnology experience (1-3 years).
Excellent salary and benefits, which include health, dental, paid holidays, vacation, stock options and a 401(k) plan. EOE
For more information, see www.DNA20.com.
Please send applications to hr@dna20.com. Phone calls NOT accepted.
Must have at least a B.Sc. degree in biological sciences, preferably in biochemistry with a good understanding of protein and DNA. Previous work experience in a research laboratory is highly preferred. The position requires some molecular biology techniques such as basic PCR, cloning, plasmid DNA preparation; growing bacteria culture and maintaining insect cell culture for protein expression; and protein purification using affinity resins and column chromatography. Tissue culture experience is a valuable asset.
BioPhase Solutions specializes in recruiting top talented professionals for San Diego’s Scientific community. We are currently looking for a Research Associate II to work for a leading San Diego biotechnology company.
Research Associate II
Assists with the development of diagnostic assays and analytical methods for the transfer of technology to the Clinical Laboratory in an interdisciplinary R&D department.
ESSENTIAL DUTIES AND RESPONSIBILITIES
* Performs experimental procedures from written SOP’s
* Assists in the development of new assays
* Contributes to the improvement of existing assays and in the development of new tests.
* Assists in the analysis of data utilizing Microsoft Access, Excel and other graphing programs.
* Maintains databases as needed
* Performs experiments utilizing molecular biology procedures such as nucleic acid extraction, PCR, RT-PCR, and hybridization assays
* Performs experiments utilizing immunological procedures such as immunostaining, immunoassay and Western Blot techniques
* Assists with assay transfer to the Clinical Laboratory
* Maintains and troubleshoots research instrumentation and suggests upgrades as required
* Confers with department staff regarding research and prepares research summaries
* Assists in research and evaluation of new technologies
EDUCATION and/or EXPERIENCE
Position generally requires a bachelor’s degree (B.A./B.S.) in the biological sciences from four-year college or university; with 2-5 years research and/or laboratory experience or a M.S. degree with 0-2 years of research laboratory experience in molecular biology and/or immunochemistry experience and must have hands on experience in performing immuno- and nucleic acid assays, and preparing reagents and/or analytical chemistry and instrumentation experience (e.g., HPLC). Experience in working in GLP/FDA/CLIA regulated atmosphere preferred.
Local candidates only will be considered at this time. If you are not local but plan to relocate, please let us know.
EMD Serono, Inc., an affiliate of Merck KGaA, Darmstadt, Germany, is a leader in the US biopharmaceutical arena, integrating cutting-edge science with unparalleled patient support systems to improve people’s lives. The company has strong market positions in neurodegenerative diseases, MS and endocrinology. EMD Serono is also a leader in fertility treatments. With a clear focus on the patient and a leadership presence in the biopharmaceutical industry, EMD Serono’s US footprint continues to grow, with more than 1000 employees around the country and fully integrated commercial, clinical and research operations in the company’s home state of Massachusetts.
Description
EMD Serono is currently looking for a motivated and talented scientist to expand the Neurodegenerative Diseases group in Cambridge, MA.
The purpose of the position is to conduct experiments under routine supervision using disease-relevant in vitro models to support drug discovery project teams for the treatment of Parkinson’s disease.
*It is anticipated that this position will move to Billerica in 2011.
KEY TASKS & RESPONSIBILITIES
This individual will be an integral part of a team that will use molecular, genetic, imaging and biochemical techniques to investigate the molecular mechanisms of nervous system disorders and to participate in drug discovery projects. A background in neuroscience or neurodegenerative models related to Parkinson’s disease is desirable.
The incumbent is expected to contribute to studies for multiple projects and to present his/her research internally in group settings. The candidate must have the ability to work collaboratively with others and independently perform and analyze in vitro experiments in line with assignments from his/her supervisor.
Specific responsibilities include:
Generates and characterizes stable cell lines for the development of disease-relevant cell models
Prepares and maintains primary neuronal cultures (including dissection)
Develops cell-free and cell-based assays for the identification of lead molecules and for mechanism of action studies
Performs data analysis, interpretation of results and trouble-shooting
Prepares written documents for internal reports
Gives data presentation to research teams
Expected to be familiar with technical and scientific literature pertaining to assigned project
Supports general laboratory maintenance and safety
Qualifications
EDUCATION / LANGUAGES
B.S./B.A. in biological sciences with 2 - 5+ years related industry/research experience or M.S. with 2+ years related industry/research experience. Degree with an emphasis on neurobiology is preferred.
Verbal and written fluency in English is required
PROFESSIONAL SKILLS & EXPERIENCE
Proficiency in cell culturing and aseptic techniques
Experience in working with DNA and RNA (e.g. cloning, purification, PCR)
Experience with protein expression and analysis (e.g. cell transfection, Western blot, immunocytochemistry, subcellular fractionation)
Familiarity with multiple screening platforms (e.g. ELISA, fluorescence/luciferase-based assays) and use of plate readers
Pharmacology experience with evaluating drug effects in vitro
High level of computer literacy (e.g. Excel, Vector NTI, Prism)
PERSONAL SKILLS & COMPETENCIES
Highly self-motivated, organized and detail-oriented
High level of flexibility and adaptability to a changing environment
Excellent oral and written communication skills.
Must be able to work in a team
Click the link below and open the door to the future by submitting your resume today!
Dana-Farber Cancer Institute is looking for a Research Technician to join their team!
Candidates should have a firm understanding or prior experience with molecular biology techniques, including PCR, genotyping, cloning and tissue culture. Be able to work with rodents and organize large mouse breeding colonies.
Job Qualifications
BA, BS or higher degree.
Schedule
Full-time, 40 hours
If interested please visit our website at: www.dana-farber.org and apply to req number 19572
Summary -Senior Research Associate/ Associate Scientist need to work in a clinical oncology group. Perform validation of new clinical molecular assays using PCR, DNA sequencing and other modern molecular analysis techniques. Perform quality control activities including incoming reagent qualification, instrument performance verification, temperature monitoring, pipette calibration, etc. Strong background in molecular biology techniques (standard and real-time PCR, DNA sequencing, automated nucleic acid isolation, etc). This is a temp to hire on direct position
One of San Diego’s best biotech companies to work for is seeking a few Research Associates to join their team for 6+ months. Please submit your resume and references as a word document if you are interested in applying.
Research Associate I
Duration: ASAP-9/1/10 (may be extended)
Pay: $15-17/hr, DOE
Job Description:
-Duties will include preparing and operating amplified testing, both automated and manual.
-Candidates will perform simple data analysis and notebooking.
-Conducts basic laboratory bench experiments.
-Participates in analysis and organization of data for presentation.
-Writes experimental summaries and technical reports for own data.
-Completes paperwork by assigned completion dates.
-Carries out assigned laboratory tasks.
-Monitor and maintain laboratory notebooks.
-Operate lab equipment and perform routine maintenance/repair.
Requirements:
- BS in Molecular Biology, Microbiology, Biochemistry, Biology or related field and Minimum 1-2 years industry experience
Brigham and Womens Hospital (BWH) is internationally known as a leader in cutting-edge research and technology and its commitment to patient-centered care. BWH has a rich legacy of excellence and has been consistently recognized as one of Americas best hospitals by US News and World Report.
GENERAL SUMMARY:
An animal research technician position is available in the laboratories of Benjamin Ebert, MD, PhD and Sandra McAllister, Ph.D. at Brigham and Women’s Hospital and members of Harvard Stem Cell Institute and the Broad Institute and Dana Farber/Harvard Cancer Center. Our laboratory uses genomics and a range of molecular and cellular biological techniques to elucidate the molecular basis of cancer and hematologic disorders and to develop and test novel therapeutics. We are looking for enthusiastic, self-motivated individuals who thrive in a fast-paced environment and can interact well with others as part of a team.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
1. Perform basic and advanced animal work including: maintain breeding colonies, injections, surgery, aseptic technique, bone marrow transplantation, tumor measurements, drug delivery, tissue harvesting and processing.
2. Perform experiments, which may be moderate to complex with increasing independence.
3. General knowledge of experimental design
4. Record and enter data into commonly used data analysis programs.
5. Familiarity and compliance with animal vivarium policies and procedures.
6. Maintain and perform experiments with cells in tissue culture, genomic DNA preparation, PCR reactions, gel electrophoresis, and reagent preparation.
7. Help to prepare presentations and written articles for publication.
8. Prepare laboratory reagents, chemicals, instruments, and maintain equipment.
9. Maintain supplies inventory in accordance with departmental procedures.
10. All other duties, as assigned.
QUALIFICATIONS:
Experience with general animal handling and surgical techniques are required. BA/BS with significant biological/physical science coursework are highly recommended. . Experience with techniques in molecular biology, cell biology, or computational biology is desirable.
Two years experience required.
SKILLS/ABILITIES/COMPETENCIES REQUIRED:
Must be able to logically and effectively structure tasks and set priorities.
Computer literacy.
Sound analytical and organizational skills.
Good oral and written communication skills.
Ability to identify potential problems and trouble-shoot solutions.
Demonstrated ability to analyze data and to think critically about experimental design.
SUPERVISORY RESPONSIBILITIES:
May be responsible for training and orienting new staff in animal husbandry and biochemical/molecular techniques.
WORKING CONDITIONS:
Laboratory environment: works with animal colonies, and occasionally works with radioactive isotopes, toxic chemicals, biohazards, and substances emitting unpleasant odors.
Artemis Health is an early-stage company dedicated to the development of non-invasive prenatal diagnostic tests. Our mission is to develop diagnostic tests that provide women, their families and healthcare providers with accurate and timely information about fetal and maternal health. We do this by developing and commercializing non-invasive and accurate prenatal diagnostic tests for use in early pregnancy, for all women.
Our company is located in San Carlos, CA. We are looking for talented people with proven skills in their discipline who enjoy working in a collaborative environment to further advances in maternal and fetal health care. This opportunity to work within a small entrepreneurial team offers tremendous growth opportunities, with competitive benefits and compensation.
We are seeking a Senior Scientist who is highly motivated to join our team in developing non-invasive prenatal genetic screening products.
Job Description:
- Perform/optimize and validate laboratory procedures associated with plasma DNA isolation from maternal blood and downstream genetic analyses.
- Develop and launch new diagnostic products and technologies by initiating, directing and executing scientific research and/or development strategies within the research team or via individual studies.
- This role is expected to manage several projects and direct reports; be highly flexible and deliver results against aggressive timelines.
Requirements:
- Ph.D. in molecular biology, genetics or related field.
- Minimum 3-5 years industrial experience in diagnostics assay development or biotechnology product development required.
- Experience in genetic and/or genomic analyses, including quantitative PCR, STR or SNP assays, familiarity with digital PCR e.g. the Fluidigm chip platform preferred.
- Experience in next generation sequencing (Solexa/Illumina platform) and data analysis strongly desired.
- Demonstrated ability to be well organized, work independently, plan and execute experiments and interpret results to high scientific rigor.
- Excellent communication, organizational, problem-solving and time management skills are essential.
To be considered for this opportunity, please submit your resume to hr@artemishealthinc.com.
Artemis Health, Inc. is an equal opportunity employer.
The successful candidate will perform biological and biochemical experiments aimed at the study of dengue virus biology and characterization of candidate anti-dengue virus inhibitors. This includes in vitro tissue culture experiments as well as experiments performed in murine models of virus infection/replication and pathogenesis. Laboratory techniques will include plasmid preps, PCR, real-time PCR (QPCR) and real-time RT-PCR (qRT-PCR), cloning; Southern, Northern, Western blot; immunoprecipitation; immunofluorescent staining, fluorescence microscopy; cell culture, and viral plaque assays. Initially, the candidate will be responsible for assisting current lab members with their projects and will also be responsible for helping with general lab tasks and maintenance. As the successful candidate demonstrates proficiency and efficiency in the lab, opportunities to work more independently will be available. The successful candidate will also perform related duties as required. A willingness to learn and a keen interest in experimental science are essential. This is a one-year grant funded position.
Basic Qualifications: College background or equivalent work experience in experimental science; 1-2 years related work experience (relevant coursework may count towards experience).
Additional Qualifications: Undergraduate degree in biology or 2 or more years in an academic research setting; prior experience in a research laboratory; comfort working with and around BL2 viruses, including dengue virus, hepatitis B, hepatitis C, poliovirus; prior experience with standard molecular biology and cell biology is preferred; tissue culture experience, virology experience and experience working with rodent models is preferred, but a willingness to learn these techniques is an acceptable substitute.
Pre-Employment Screening: Identity
All applicants must apply via our website (please see requistion number 20468BR):
